Drug Discovery and Design

Our understanding of how major diseases, like cancer, work at the biological level has advanced by leaps and bounds over the last decade. Today, U of T scientists and bioengineers are applying that understanding to develop new drugs and targeted therapies to more safely and effectively treat individuals with rare and complex diseases.

U of T prof’s AI startup, Deep Genomics, raises US$180 million: The Globe and Mail

U of T prof’s AI startup, Deep Genomics, raises US$180 million: The Globe and Mail

Photo of genetic testing U of T and health industry leaders urge investment in biomedical innovation

U of T and health industry leaders urge investment in biomedical innovation

An illustration of DNA: a shape like a ladder twisted into a spiral, with the rails and rungs made up of tiny spheres. ‘Genome Archeologists’ at U of T and UHN activate immune response against cancer

‘Genome Archeologists’ at U of T and UHN activate immune response against cancer

Ruby Sullan, an assistant professor at U of T Scarborough, says her team has designed an approach that can curb the onset of drug resistance in bacteria (photo by Ken Jones) Nanoparticles show promise in defeating antibiotic-resistant bacteria, U of T researchers find

Nanoparticles show promise in defeating antibiotic-resistant bacteria, U of T researchers find

The researchers say drugs derived from natural compounds, as opposed to the synthetic ones, tend to be more effective because "they were honed by evolution to work on living cells" (photo via Wikipedia Commons) Drugs from nature: Researchers from U of T, Japan mine microbial compound library for new therapeutics

Drugs from nature: Researchers from U of T, Japan mine microbial compound library for new therapeutics

Hand holding pipette with CBD oil on wooden table with copy space In a bid to develop future medicines, U of T study sheds light on complex, plant-based compounds

In a bid to develop future medicines, U of T study sheds light on complex, plant-based compounds

Photo of Shana Kelley U of T researchers enlist tiny biomagnets for faster drug discovery

U of T researchers enlist tiny biomagnets for faster drug discovery

Photo of Oren Kraus U of T grad’s AI startup raises US$1.5 million to accelerate cancer drug discovery

U of T grad’s AI startup raises US$1.5 million to accelerate cancer drug discovery

Photo of Hirano U of T researchers develop new generation CAR T-cells for cancer therapy

U of T researchers develop new generation CAR T-cells for cancer therapy

Patrick Gunning, a principal investigator at U of T Mississauga's Centre for Medicinal Chemistry Advancing Drugs to Fight Cancer and Other Diseases

Advancing Drugs to Fight Cancer and Other Diseases